| Summary: | 碩士 === 國立中興大學 === 資訊網路多媒體研究所 === 99 === Micro RNAs(miRNAs) are a hairpin-type small RNA. They exist in animals'', plants'' and virus'' genome. miRNA regulation of gene expression is involved in embryonic development, cell proliferation, cell differentiation, cell dying, chromosome structure, and antiviral response. According to previous studies, human genome contains more than 50% of repetitive sequences, and more than 45% of these repetitive sequences are derived from transposable elements. The transposition of the transposable element, TE, which is also called the mobile element will lead to mutation in the genome structure and affect the translocation at the gene expression. The purpose of this study is major in the analysis of miRNA gene sequences, which may be derived from the transposable elements. This kind of miRNAs is called TE-derived miRNAs. We also target the sequences of the TE-derived miRNAs to the specific messenger RNAs in order to observe the distribution of transposable elements.
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