Evaluation of the Antimicrobial Activity and Biocompatibility of Silver Nanoparticles Immobilized on Nano Silicate Platelets and the Nanocomposites with Polyurethane

• Main Authors: Shing-Da Li, 李星達
• Other Authors: 戴憲弘
• Format: Others
• Language: zh-TW
• Published: 2011
• Online Access: http://ndltd.ncl.edu.tw/handle/97706806406467026661

碩士 === 國立中興大學 === 化學工程學系所 === 99 === Silver nanoparticles have been known for bactericidal abilities. However, particle size and dispersion will affect the antibacterial potency, and nanoparticles may cause injuries to the biological system. Therefore, the issue about safety and antibacterial property of concentration of silver nanoparticles for biological application should be evaluated. The nanomaterials used in this article were synthesized using nanosilicate platelets (NSP) as the dispersing agent for immobilization of silver nanoparticles (AgNPs/NSP). Polyurethane-AgNPs/NSP nanocomposites from a polyether-type waterborne polyurethane (PU) containing various concentration of AgNPs/NSP were prepared. AgNPs/NSP were found to have a high antibacterial efficacy, low cytotoxicity and non-hemolytic effect at the concentration of 10 ppm. Polyurethane-AgNPs/NSP nanocomposites demonstrated superior microbiostatic ability as well as non-toxicity.