A Preliminary Study on Medical Application of Laser Doppler Flowmetry – Effects of Thermal, Mechanical and EMF Exposure on Blood Perfusion of Hand Vascular

• Main Authors: Chung-yi Tu, 涂崇一
• Other Authors: Kuen Ting
• Format: Others
• Language: zh-TW
• Published: 2011
• Online Access: http://ndltd.ncl.edu.tw/handle/04156064189168907540

碩士 === 龍華科技大學 === 工程技術研究所 === 99 === The Laser Doppler Flowmetry technology has been successfully applied to various peripheral blood circulation, especially to microcirculation related diseases in the past decades due to its noninvasive characteristics. Inspired by those studies related to the test of Raynaud’s syndrome, we aim our purpose in this study, to explore our experience with its application through identifying the hand vascular blood perfusion with various test environments such as low temperature, high mechanical load, and different RF EMF exposures. A LDFI(Laser Doppler Flowmetry Imager) surveillance of a healthy man’s hand under the comfort test environment of 23'C has been made to acquire blood perfusion of a normal hand vascular as a controlled database of the test. We then, apply the LDFI scan to survey the tested hand under the environments with increasing incremental variation of temperature, mechanical load and RF EMF exposures. Observation of the responded blood perfusion along with its space and time related behaviors have been made, simplified sensitivity analysis and parametric trend analysis have been made accordingly. The test result confirms to those pathogenesis studies of the human body under the cold provocation test, blockage of local vascular blood perfusion for 1~3 minutes has been found due to the autonomic nervous system temperature control function. Yet, similar results also found in the tests of mechanical load and RF EMF exposures. It implies that human body also responds and functions properly corresponding to the energy stimulation. A group of 11 examiners has been surveyed with the energy stimulation experiments. Data has been acquired by the MoorLDI-2λ image review module and analyzed by Matlab Statistic Toolbox with ANOVA algorithm. Through this study, we also established a typical LDFI data inquiry and analysis SOP(Standard Operating Procedure) for similar experimental needs in the future.