| Summary: | 碩士 === 高雄醫學大學 === 職業安全衛生研究所 === 99 === According to the previous studies, house dust mite is the primary source of antigen in indoor environment. For children, sensitization to house dust mite allergens is strongly associated with asthma.
There are four objectives of this study. First one, we want to investigate the concentrations of house dust mite allergen of asthma and non-asthma school children’s houses in house dust and air in Kaohsiung city. Second, we plan to evaluate the correlations of dust and air samples. Third, we try to assessment the correlations between mite in dust and air samples and health effects. And the last one is to assessment the correlations between mite in dust and air samples and other factors.
From April to October in 2010, we collected 240 dust samples and 120 air samples from 60 schoolchildren’s houses in Kaohsiung city. We used vacuum cleaner and cellulose extraction thimbles to sampling dust from living room floor, bedroom floor, mattress and pillow. And we used a pump and Teflon filters to sampling the concentration of Der p 1 antigen in air in bedroom for 24 hours. We also investigated some environmental factors in housed, like the concentration of fungi, bacteria, endotoxin, and temperature etc. Besides, we evaluated lung function, exhaled CO and specific IgE from children.
In dust samples, the detected rates of Der p 1 antigen in living room floor samples was 67%, in bedroom floor samples was 84%, in mattress samples was 98% and 93% in pillow samples. The detected rates of air samples were both 57% in living room and bedroom.
The concentration of Der p 1 antigen in bed samples (the mean concentration of mattress and pillow samples) (1817.83 ng/g) was significant higher than floor samples (the mean concentration of living room floor and bedroom floor samples) (240.59 ng/g), p < 0.001.
Whether it is the first day, the next day or two days on average, VC% of children were significant correlation with the concentration of Der p 1 antigen in bedroom samples in air. Children who allergic with house dust, the concentration of Der p 1 antigen in their bedrooms in air samples was significant higher than non allergic children.
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