| Summary: | 碩士 === 義守大學 === 機械與自動化工程學系碩士在職專班 === 99 === Patient controlled analgesia (PCA) is a method of pain control that gives the patient to control their pain. Traditionally, in PCA, a pump called the patient controlled analgesia pump - that contains a syringe of pain medication as prescribed by a doctor is connected directly to a patient''s intravenous (IV) line. In principle, the pump is set to deliver a small, constant flow of pain medication. Additional doses of medication can be self-administered as needed by the having the patient. Other times, a patient can control when he or she receives pain medication and does not receive a constant flow. Currently, micromachining technology has provided a means to miniaturize microfluidic applications on PAC. Hence, an efficient and precise deformation mechanism of membrane in microstructures has been a challenging work for miniaturized systems. Many methods have been developed recently for this purpose. There have been several ways to actuate thin membrane in microchip. Among them, the pneumatic flexible polymer membrane is one of the most commonly used and reliable methods. However, the deformation characteristics of pneumatic flexible polymer membranes, i.e., the actuated mechanism cannot have been successfully demonstrated in the previous researches.
In this study, we want to design and fabricate a pneumatic micropump in PCA. For the disposable purposed, a kind of polymer-PDMS (polydimethylsiloxane) is chosen, and its flexible material property is also excellent to form the movable membrane of the micro-actuator. The external air is input into air chamber to activate pneumatically the PDMS deformed structures to get the operation purpose. Firstly, the theoretical analysis was employed to investigate the deformed mechanism and to identify how the deformed behaviors affected by the different operating parameters. Next, the parameters of operating air pressures and geometry sizes will be then measured experimentally to verify theoretica results. Finally, the results could be provided a foundation of the design and development of PDMS membrane actuator, i.e. pneumatic micropump, applied on PCA in the future.
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