| Summary: | 碩士 === 中原大學 === 生物醫學工程研究所 === 99 === According to the statistics from World Health Organization in 2007, one third of adults had conduct of cigarette smoking in the worldwide. Cigarette smoking produce many kinds of chemical compounds, these compounds contact with the upper aerodigestive tract first, and then through the upper aerodigestive tract into human body. Therefore, smoking could harm the mucosa of aerodigestive tract, result in the oral, laryngeal, esophageal and respiratory tract dysfunction, which may affect the ability to swallowing. Swallowing inability could induce malnutrition, dehydration, pneumonia or even death.
The aim of this study was to examine whether smoking has an impact on the ability to swallowing. We studied 38 healthy volunteers, and divide they into two groups: smokers(n=18) and non-smokers(n=20). We assessed the swallowing abilities using surface electromyography(sEMG) and thyroid cartilage motion analysis, and using water swallowing test with swallowing parameters (latency time, total time, amplitude, excursion time, jitter and SM amplitude) in both smoking and non-smoking subjects. The result showed that the total time and the jitter had significant difference(P<0.05) in dry, 2ml, 5 ml (room temperature), 10 ml and 5 ml (4oC). The amplitudes also had significant difference in all swallowing boluses. The results illustrated that the laryngeal elevation in an earlier time, and the pharyngeal swallowing time was prolonged in smoking group. Therefore, we suggested that smoking may increase the upper airway reflex sensitivity and reduce the ability of pharyngeal transit.
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