Associations Among Metabolic Syndrome , Depression, Excessive Sleepiness, and Health-related Quality of Life:Gender Difference in The Mid-aged and Elderly

• Main Authors: Liang-Jen, 陳亮仁
• Other Authors: Hua Ting
• Format: Others
• Language: zh-TW
• Published: 2011
• Online Access: http://ndltd.ncl.edu.tw/handle/89020210347420436558

碩士 === 中山醫學大學 === 醫學研究所 === 99 === Objective： The aim of this study is to exam the associations among metabolic syndrome, depression, excessive sleepiness, and health-related quality of life (HRQoL).We hypothesized that metabolic syndrome would be associated with lower HRQoL score and higher depression and excessive sleepiness score. Methods and Materials： 378 eligible mid-aged and elderly participant were recruited to our study when their adult health examination, provided by Taiwanese National Health Insurance Company, were completed. We also offer additional and free HDL measurement to meet the criteria of metabolic syndrome. The Medical Outcome Study, short form-36 (SF-36) Beck Depression Inventory 2nd edition (BDI II) and the Epworth sleepiness scale(ESS)wese used to assess HRQoL, the level of depression, and the level of sleepiness, respectively. Differences in HRQoL and in clinical and psychological characteristics were compared among participants with and without metabolic syndrome. Multiple variances regression was used to determine the predictors of HRQoL, depression, and excessive sleepiness. Results： Metabolic syndrome was associated with lower scores on the subscales of SF-36 and on the physical component summary (PCS) score only in female. Depression and age are the top two significant predictors of lower score of SF-36 by multiple variance regression analysis. For ESS score, depression and diabete mellitus (DM) history were two predictors in female, whereas BMI and age in male. After adjusting other potential confounding variances, the presence of metabolic syndrome has little effect on depression and sleepiness score . Conclusion and Suggestion： The results indicate that metabolic syndrome is associated with poor HRQoL solely in women, which might be accounted mainly for by physical instead of mental health. That gender difference on predictors of ESS score might imply heterogeneous effect on ESS score between difference gender.