| Summary: | 碩士 === 嘉南藥理科技大學 === 化妝品科技研究所 === 99 === The purpose of this study was the preparation and investigation of sunscreen containing polymeric microcapsules. Different microcapsules were obtained by emulsification/internal gelation. First the sunscreen Benzophenone-4 (BP-4)/sodium alginate (SA) solution was mixed with CaCO3 solution, then the solution was added into liquid paraffin of span80 to get W/O type reversal micelles emulsion. The glacial acetic acid was dropped into emulsion to initiate polyelectrolyte gelation between Ca2＋and carboxylate of SA to form microcapsules. The parameters included amount of span80, sodium alginate and BP-4 were investigated, for discussing the average particle size, specific surface area, particle size distribution, encapsulation efficiency and loading capacity of the microcapsules.
The structure and morphology of microcapsules depended mainly on Span80 and SA concentration. BP-4 released and photodegradation mechanism followed very well with first order model. And the SPF value was promoted obviously after encapsulation.
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