Investigation of New Synthesis Methodology forSteroid Derivatives and Bioactivity Evaluation

碩士 === 中國醫藥大學 === 藥物化學研究所碩士班 === 99 === A one-pot ethynylation and catalytic desilylation reaction was developed for the synthesis of α-C17-ethynyl-containing steroid derivatives (e.g. mestranol and levonorgestrel). Addition of trimethylsilylacetylide to the carbonyl group at C-17 of the steroids yi...

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Bibliographic Details
Main Authors: Wen-Che Tseng, 曾文哲
Other Authors: Fung-Fuh Wong
Format: Others
Language:en_US
Published: 2011
Online Access:http://ndltd.ncl.edu.tw/handle/32236417910872913141