Real-time PCR panels for detection of mutations responsible for failure of EGFR-targeted therapy in colorectal cancer

Real-time PCR panels for detection of mutations responsible for failure of EGFR-targeted therapy in colorectal cancer

碩士 === 長庚大學 === 醫學生物技術暨檢驗學系 === 99 === Cetuximab and panitumumab are major drugs against epidermal growth factor receptor (EGFR) in colorectal cancer. However, mutations in downstream of EGFR signaling pathway, including KRAS, BRAF, and PIK3CA, abolish the response of anti-EGFR therapy. Therefore, t...

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Bibliographic Details
Main Authors:	Chia Yu Chang, 張家瑜
Other Authors:	C. C. Chiou
Format:	Others
Published:	2011
Online Access:	http://ndltd.ncl.edu.tw/handle/29195640825955655361

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