Prospective Analysis of the Change in Quality of Life on Breast Cancer Female with Breast Reconstruction

• Main Authors: Li Fen Chao, 趙莉芬
• Other Authors: H. E. Liu
• Format: Others
• Published: 2011
• Online Access: http://ndltd.ncl.edu.tw/handle/65632904839695579809

博士 === 長庚大學 === 臨床醫學研究所 === 99 === Objective: The aim of the study was to prospectively evaluate the patient-reported outcome on the long-term aspects of health-related quality of life (HRQoL) in the breast cancer patients who undergoing/underwent mastectomy with or without reconstruction. Methods: Participants who were recruited from three hospitals of the north of Taiwan completed modified Breast-Q questionnaire before surgery and then again 1, 3, 6, and 9 months after surgery. Questionnaire assessed four dimension, including body image, psychosocial, sexual, and physical well-being. The differences between postoperative and preoperative scores were compared across timing or procedure types using General Estimating Equation and analysis of covariance. Results: For the breast reconstruction (n=61) cohort, had significantly greater gains were observed in all subscales. The mastectomy alone group (n=39) was getting worse all. In the cohort with delayed reconstruction (n=29), significant improved scores were observed in all subscales of Breast-Q. Moreover, delayed autologous tissue reconstruction patients noted greater gains in body image, sexual and physical well-being compared with women choosing delayed expander-implant reconstruction. Similarly, among women receiving immediate reconstruction (n=32) eventually returned to baseline levels except psychosocial well-being. However, no significant effects of procedure type on these changes over time existed. In the brief, the HRQoL of the women with breast reconstruction had been improved or recovered significantly since three to six months operation follow-up. Conclusions: In the long term, both immediate and delayed breast reconstructions provide substantial well-being of HRQoL for mastectomy patients. These long-term data have important implications for women’s health. And, the Breast-Q can be used to appropriately assess the impact and effectiveness of breast surgery from the patient’s perspective.