Development of Fourier Domain Mode Locking laser for Optical Coherence Tomography Study

碩士 === 長庚大學 === 電機工程學系 === 99 === In this study, we developed a Fourier domain mode locking laser (FDML) used as the light source of swept-source optical coherence tomography (SS-OCT) system. Furthermore, in this thesis, the SS-OCT system was implemented for the defect inspection of industrial produ...

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Bibliographic Details
Main Authors: Feng Yu Chang, 張峰瑜
Other Authors: M. T. Tsai
Format: Others
Published: 2011
Online Access:http://ndltd.ncl.edu.tw/handle/76943281471556203043
Description
Summary:碩士 === 長庚大學 === 電機工程學系 === 99 === In this study, we developed a Fourier domain mode locking laser (FDML) used as the light source of swept-source optical coherence tomography (SS-OCT) system. Furthermore, in this thesis, the SS-OCT system was implemented for the defect inspection of industrial products, visualization of the structures of human skin, and heart function evaluation of Drosophila. The light source is a key component in OCT system, which is related to the axial resolution and imaging speed of SS-OCT system. In this thesis, the home-made FDML laser can provide a scan rate of 240 kHz, more than 20 mW in output power, and a scanning range of 80 nm centered at 1310 nm. Compared with the commercially swept source, our FDML laser can achieve higher scan rate and phase stability. Additionally, the motion artifacts due to the unconscious movement from the sample can be greatly reduced with a FDML laser. Additionally, an SS-OCT system was implemented to scan the ITO conducting glass. With OCT scanning, the defects can be clearly identified at various depths. Several parameters in addition to morphological information can be estimated simultaneously, including the thickness of the glass substrate, the refractive index, reflection coefficient, and transmission coefficient, all of which can be used to evaluate the quality of ITO conducting glass. Furthermore, the different layer structures of human skin can be clearly identified with OCT scanning results, such as the sweat glands, hair follicles, epidermis, and dermis. Finally, SS-OCT system was used to record and analyze the heart beats of Drosophila under the different methods for immobilizing flies during OCT scanning.