| Summary: | 碩士 === 淡江大學 === 化學學系碩士班 === 98 === One of the problems in traditional biochemical testing methods is that it requires labor power and complicated detecting methods; hence, it often takes several days to get results. However, to obtain accurate data from tests in a short period of time is essential for emergency patients and medicinal issues. Therefore, a real-time instrument with accurate detection is indispensable. The object of the study is to present a real-time sensing system with precision and sensitivity.
The study is an innovating electrical sensing mode which adopts antibody - antigen binding method. The research team learns remarkable difference between specificity and non-specificity between antibody and antigen by observing electrical signals produced by some medical testing markers and drug tests, such as α-Fetoprotein (AFP), (+, -)-3, 4-Methylene- dioxyphenylisopropylamine (MDMA, Ecstasy), when using the electrical sensing mode in which we not only compare the results measured before and after a couple of minutes but also experiment with different concentrations. Qualitative analysis has been achieved after a series of testing. Moreover, we also have done tests in clinical environment as far as experiment method to be concerned. The results have shown significant and positive meanings since our research is valuable when being applied to test for various clinical indicators. Our research team will keep making effort to invent cheaper and smaller instruments in order to improve everyone’s life.
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