| Summary: | 碩士 === 國立臺北科技大學 === 材料科學與工程研究所 === 98 === Two kinds of calcium sulfate and calcium phosphate bio-ceramics, because of excellent biocoMPatibility, non-toxic cell, and for major components of the human skeleton, has been extensively studied and used in orthopedics and dental surgery such as bone defect repair materials. Calcium sulfate is a bone induction, but the absorption rate of fast. Calcium phosphate has osteoconduction, but take a long time to be absorbed, so guided bone growth is extremely slow.
This study investigated the hydrated calcium sulfate and calcium phosphate are made of composite materials, research Physical properties, Mechanical Properties, degradation rate and biocoMPatibility of the effect, and the use of SEM, EDS, XRD analysis of the materials. The establishment a group of TiO2 added to the effects in cell culture. And for material degradation results of the experiment, the establishment kinetics of reaction equation.
The results show that the calcium sulfate and calcium phosphate compound into, When the calcium sulfate content of 70 ~ 90wt%, the mechanical strength of the best, shows that have a strengthening effect of calcium phosphate additions. Aspects of cell activity, when the calcium phosphate concentration increases, the cell activity promotion, Which contain TiO2, this group of specimens, but also get a better cell activity value, showing a high biocoMPatibility of TiO2.
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