Identification of Cancer Genes - A Comparison of t-test and SAM

碩士 === 亞洲大學 === 生物資訊學系碩士班 === 98 === This research aims at comparing the performance of two approaches in predicting cancer genes, i.e oncogenes (OCG), tumor suppressor genes (TSG) and cancer-related genes (others), for three different types of cancers, namely, liver cancer, esophaguae cancer and br...

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Main Authors: Che-Hau Chang, 張哲豪
Other Authors: Ka-Lok Ng
Format: Others
Language:zh-TW
Published: 2010
Online Access:http://ndltd.ncl.edu.tw/handle/46330125851926716720
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spelling ndltd-TW-098THMU81120062015-11-02T04:04:17Z http://ndltd.ncl.edu.tw/handle/46330125851926716720 Identification of Cancer Genes - A Comparison of t-test and SAM 預測癌症差異性表達基因- t-檢定與SAM方法比較 Che-Hau Chang 張哲豪 碩士 亞洲大學 生物資訊學系碩士班 98 This research aims at comparing the performance of two approaches in predicting cancer genes, i.e oncogenes (OCG), tumor suppressor genes (TSG) and cancer-related genes (others), for three different types of cancers, namely, liver cancer, esophaguae cancer and breast cancer. Gene expression data are downloaded from EBI ArrayExpress. The student t-test approach and the Significance Analysis of Microarrays (SAM) are employed to identify cancer genes. It is found that t-test performs better for esophagaue caner and breast cancer, while SAM performs better for liver cancer. The web site of studying results is available at http://ppi.bioinfo.asia.edu.tw/P_Cancer_T_SAM/ Ka-Lok Ng 吳家樂 2010 學位論文 ; thesis 60 zh-TW
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language zh-TW
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description 碩士 === 亞洲大學 === 生物資訊學系碩士班 === 98 === This research aims at comparing the performance of two approaches in predicting cancer genes, i.e oncogenes (OCG), tumor suppressor genes (TSG) and cancer-related genes (others), for three different types of cancers, namely, liver cancer, esophaguae cancer and breast cancer. Gene expression data are downloaded from EBI ArrayExpress. The student t-test approach and the Significance Analysis of Microarrays (SAM) are employed to identify cancer genes. It is found that t-test performs better for esophagaue caner and breast cancer, while SAM performs better for liver cancer. The web site of studying results is available at http://ppi.bioinfo.asia.edu.tw/P_Cancer_T_SAM/
author2 Ka-Lok Ng
author_facet Ka-Lok Ng
Che-Hau Chang
張哲豪
author Che-Hau Chang
張哲豪
spellingShingle Che-Hau Chang
張哲豪
Identification of Cancer Genes - A Comparison of t-test and SAM
author_sort Che-Hau Chang
title Identification of Cancer Genes - A Comparison of t-test and SAM
title_short Identification of Cancer Genes - A Comparison of t-test and SAM
title_full Identification of Cancer Genes - A Comparison of t-test and SAM
title_fullStr Identification of Cancer Genes - A Comparison of t-test and SAM
title_full_unstemmed Identification of Cancer Genes - A Comparison of t-test and SAM
title_sort identification of cancer genes - a comparison of t-test and sam
publishDate 2010
url http://ndltd.ncl.edu.tw/handle/46330125851926716720
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