| Summary: | 碩士 === 國立臺灣大學 === 臨床牙醫學研究所 === 98 === Objectives: The aim of this study was to develop a fluoride releasing strip for dental clinicians to increase the effectiveness of topical fluoridation.
Moreover, this study tried to establish a molecular- based model to analyze the product on teeth enamel after fluoridation.
Methods: This multi method study used XPS, SIMS, SEM measurements in order to analyze qualitative and quantitative change of teeth enamel after use of fluoride releasing strip. And used Ion Chromatography to
determine demineralization/ remineralization rate change of enamel after fluoride strip fluoridation.
Results: The reaction reached saturation point after 8 hours use of strip. The main product was calcium fluoride. Fluoride strip effect deeper on enamel samples witch pretreated with demineralization solution then
sound enamel samples. Using XPS depth profile survey, we found that the depth of fluoride infiltration is about 7.2μm on sound enamel sample
and 17.6μm in demineralized enamel sample. It seems that topical fluoridation inhibited enamel demineralization more effectively then increased enamel remineralization.
Key Word: topical fluoride, dental enamel, surface
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