In vitro compound screening for SCA17 and interaction analysis between expanded TBP and HMGB1

碩士 === 國立臺灣師範大學 === 生命科學研究所 === 98 === Neurodegenerative diseases such as hereditary spinocerebellar ataxias (SCAs) type 1, 2, 3, 6, 7, 17 and Huntington's disease are linked to abnormally expanded polyglutamine (polyQ) tract in the respective proteins. The polyQ expansions cause a conformation...

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Bibliographic Details
Main Authors: Shu-Ting Yang, 楊淑婷
Other Authors: Guey-Jen Lee-Chen
Format: Others
Language:zh-TW
Published: 2010
Online Access:http://ndltd.ncl.edu.tw/handle/62117075451669514573