Prediction of Human Multidrug Transporter P-Glycoprotein Inhibition Activity Using Pharmacophore Ensemble/Support Vector Machine Approach
碩士 === 國立東華大學 === 化學系 === 98 === P-glycoprotein (P-gp) is an ATP-dependent membrane transporter that plays a pivotal role in eliminating xenobiotics by active extrusion of xenobiotics from the cell. Multidrug resistance (MDR) is highly associated with the overexpression of P-glycoprotein (P-gp) by...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Others |
| Language: | en_US |
| Published: |
2010
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| Online Access: | http://ndltd.ncl.edu.tw/handle/46985220745933953368 |