Comparison of the disease-disease correlation and comorbidity with the genes and risk factors

• Main Authors: Cheng-Sheng Yu, 游程盛
• Other Authors: Jorng-Tzong Horng
• Format: Others
• Language: en_US
• Published: 2010
• Online Access: http://ndltd.ncl.edu.tw/handle/11751125759087722608

碩士 === 國立中央大學 === 資訊工程研究所 === 98 === A disease network has been developed in recent years. It is linked by genes and protein-protein interaction to show the relation between them and diseases. But there are still many unknown factors that have play an important role in disorders and epidemiology. We investigate the correlation between different popular diseases known by share genes on OMIM(Online Mendelian Inheritance in Man) and other risk factors such like sex and age. The chronic diseases such high blood pressure, osteoarthritis and cancers have a lot of other risk factors that affect people’s health, not just involved by genes. We not only check the diseases induced by genes from OMIM but also want to find whether the risk factors which have impacts on those diseases play a more important role in epidemiology. Maybe there are some diseases we have not found the correlation between each other. We attempt to construct a disease-disease network in a new relation and detect what doesn’t find between the diseases and human in epidemiology in Taiwan.