| Summary: | 碩士 === 國立交通大學 === 電控工程研究所 === 98 === In neuroscience, cognitive and memory is very important topic. The hippocampus is thought the main function for managing the memory system. Previous study has shown that the neuron activities in hippocampus present spatial information and provide the hypothesis of “cognitive map” for functional hippocampus. However, the correlation between spatial memory and neuron activities are not clearly defined. Therefore, understanding the function of the hippocampus in the formation of spatial memory learning process and describing this mechanism in systemic encode is our purpose.
Our research design water reward task to train the rats free running in the environment. Recorded neuron signals through the invaded electrode were examined the relationship with animal behaviors. There are two types of neurons in hippocampus: pyramidal cells and interneurons. The pyramidal cells discharge not only in specific location but also corresponding to theta (4-12Hz) band rhythm, known as phase precession. Interneurons were discovered firing emphasis in corner zone and exhibiting functional monosynaptic coupling in temporal firing and in spatial firing field with pyramidal cell. The low band variance also present in local field potential, where beta band is response to the odor-learning and theta band is response to the movement. Though those feature of neuron signals, we provide a self-organization feature map for learning process to explain animal habitual behavior involved in direction preference and variance in trajectories.
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