| Summary: | 碩士 === 國立交通大學 === 物理研究所 === 98 === Nitric oxide (NO) is a free radical playing important roles in the human body. NO produced endogenously by one cell can transmit through cell membranes and regulates the function of another cell. NO also relaxes the smooth muscle in the walls of the arterioles, regulates the blood pressure, and inhibits the aggregation of platelets. In this work, a sensing hydrogel film specific to NO is developed. The NO sensing hydrogel film is integrated with organic light-emitting diode (OLED) and silicon photo detector (PD) for real-time monitoring NO. The OLED is used to excite the NO sensing hydrogel film, and the PD is used to detect the photoluminescence (PL) from the sensing film. A fluorescent probe 11,16-bisphenyl-6,6,21,21 - tetramethyl-m-benzi - 6,21 - porphodimethenochloro-zinc(II) (BPDM–H–ZnCl) is synthesized from m-benziporphodimethene based molecule and blended with poly(2-hydroxyethyl methacrylate) to form the NO sensing hydrogel film. This sensing film is demonstrated for real-time and indicator-free detection of NO in aqueous solution. This sensing hydrogel film also shows high selectivity, sensitivity, and stability in various pH values. The integrated device is capable of sensing NO concentration variation in a real-time manner.
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