Striatal dopamine transporters in euthymic patients with bipolar disorder- a SPECT study with [99mTc] TRODAT-1
碩士 === 國立成功大學 === 行為醫學研究所 === 98 === Abstract Background: Dopamine has been implicated in the etiology of bipolar disorder. The aim of this study was to explore striatal dopamine transporter (DAT) availability in euthymic bipolar patients. Methods: Seventeen drug-free euthymic bipolar patients were...
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| Other Authors: | |
| Format: | Others |
| Language: | zh-TW |
| Published: |
2010
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| Online Access: | http://ndltd.ncl.edu.tw/handle/29275824414655094856 |
| Summary: | 碩士 === 國立成功大學 === 行為醫學研究所 === 98 === Abstract
Background:
Dopamine has been implicated in the etiology of bipolar disorder. The aim of this study was to explore striatal dopamine transporter (DAT) availability in euthymic bipolar patients.
Methods:
Seventeen drug-free euthymic bipolar patients were recruited. The availability of DAT was approximated using SPECT with [99mTc] TRODAT-1.
Results:
Compared to the controls, the euthymic bipolar patients had significantly higher availability of striatal DAT.
Conclusions:
Even for patients in the euthymic state, the DAT availability is still higher than that of the controls.
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