Central autonomic network in uremics studied by spectral analysis of simultaneous heart rate variability and electroencephalography

• Main Authors: Li-Min Liou, 劉立民
• Other Authors: Chiou-Lian Lai
• Format: Others
• Language: zh-TW
• Published: 2010
• Online Access: http://ndltd.ncl.edu.tw/handle/15220811930309972454

碩士 === 高雄醫學大學 === 醫學研究所 === 98 === Autonomic dysfunction, which is common in uremics is one of the explanation of the excess cardiovascular mortality. Some central nervous system diseases may result in autonomic dysfunction, such as Parkinson’s disease and stroke. There may be a central autonomic network (CAN) connecting with the peripheral nervous system for modulating the autonomic function. We use spectral analysis of simultaneous heart rate variability and electroencephalography to investigate the CAN in uremics. In conclusion, we found that there is CAN both in control and uremics. However, the CAN in control and uremics are different in location. We suggested that there is a switch from the use of temporal areas in control to para-sagittal areas in uremics with autonomic dysfunction. In addition, the sympathetic activity seems to correlate with alpha, theta, and delta EEG power, while the para-sympathetic activity correlates with beta EEG power.