| Summary: | 碩士 === 義守大學 === 機械與自動化工程學系碩士班 === 98 === Basic microfluidic components, such as microchannels, microvalves, micropumps, micromixers and microreactors with various novel sensors and detection platforms have been successfully applied in the microfluidics and Bio-MEMS fields. Among them, the micropumps are the most important components due to the use of sample delivery and manipulation in the microfluidic devices and systems. In this study, a new micro-pump utilizing active check-valve structures has been successfully demonstrated for sample transportation. The moving structure with an active check-valve is activated pneumatically to deform the PDMS membrane and generate a transporting of the sample streams to the detected region. Meanwhile, a theoretical analysis and a numerical simulation were employed to investigate the deformation mechanism and then confirmed by experimental data. Hence, the numerical calculations were also used to design the optimum actuated membrane. Variations of the generated flow rate with the pneumatic frequencies, actuated air pressures and operated cases are analyzed experimentally. The larger flow rates are obtained for the basic parameters such as driving frequencies and actuated air pressures depended on design features. The optimum parameters of air pressure, driving frequency, and location position of active check valve are experimentally 10 psi, 26 Hz, and 600 μm, respectively. The maximum pumping rate was found to be 532μL/min. Furthermore, the proposed micro-pump could be crucial for the transportation of the microfluidics and could be incorporated with the micro-total-analysis-systems.
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