Enhancement of Quantitative Accuracy for [18F]-Fluorodeoxyglucose PET by Corrected SUV of Injec-tion Leakage

• Main Authors: Pao-Yin Wang, 王寶英
• Other Authors: Tai-Been Chen
• Format: Others
• Language: zh-TW
• Published: 2010
• Online Access: http://ndltd.ncl.edu.tw/handle/06064592781772401491

碩士 === 義守大學 === 資訊工程學系碩士班 === 98 === Whole body 18F-FDG (2-[Fluorine-18]fiuoro-2-deoxy-D-glucose) imaging based on PET/CT (Positron Emission Tomography/Computer Tomography) is applied to observe tumor or inflammation tissue via measuring the distribution of glucose metabolism in tissue cell. The clinicians can design types of treatment planning and evaluation of curative effect through 18F-FDG PET. In general, the standardized uptake values (SUV) of lesions on PET/CT images are used to distinguish abnormal organs or tissues. However, there are numerous external factors to affect the accuracy of SUV. The influence of leakage dose on the calculation of SUV is rarely discussed in the literatures at present. This study utilizes regression approach to estimate the dosage of 18F-FDG by measuring the leakage dose of the 18F-FDG on PET/CT images. The corrected SUV (SUVcor) obtained from the regression approach can remedy underestimated SUV calculated from image (SUVimage). The proposed method is robust and efficient to enhance the accuracy of SUV on PET/CT.