Patterns of lung cancer incidence in 19 countries

• Main Authors: Yu-Tzung, 陳昱宗
• Other Authors: Yung-Po Liaw
• Format: Others
• Language: zh-TW
• Published: 2010
• Online Access: http://ndltd.ncl.edu.tw/handle/51022501950513472316

碩士 === 中山醫學大學 === 公共衛生學系碩士班 === 98 === Objective: We analyzed the incidence data of lung cancer from 1978 to 1997 among men and women between 19 countries. Methods: The data were collected from 18 countries in World Health Organization and Department of Health in Taiwan during in the period of 1978 to 1997. Age-standardized incidence rates（ASIR） were analyzed in five consecutive five-year periods and for each five-year age group in the age range 30 to 79. An age-period-cohort（APC） model were used to estimate the effects of age, generation and cohort of birth. Results: The sex ratio of the ASIR for adenocarcinoma（AC） was lower than sex ratio of the ASIR for squamous cell carcinoma（SCC） in 19 countries. The sex ratio of the ASIR for adenocarcinoma and squamous cell carcinoma in Europe（AC 3.39±1.51, SCC 14.20±10.43）is higher than in Asia（AC 1.93±0.38, SCC 6.83±1.81） or in North America（AC 1.54±0.02, SCC 3.85±0.49）. The period effects（AC） for males and females from the APC model applied to the data from the 19 countries: an increasing trend in both sexes, seen in Taiwan, France, Japan and Slovakia; a gradual increasing trend in both sexes, seen in Singapore and India; a sharply increasing trend in women, and a sharply decreasing trend in men, seen in Estonia and Iceland; a more gradual increasing trend in women, but a gradual declining trend in men, seen in USA, Canada and Italy; a decreasing trend in both sexes, seen in Spain and Australia; a gradually increasing trend in men, but a increasing trend in women, seen in England and Wales and Denmark; a relatively steady trend in both sexes, seen only in Israel; a sharply decreasing trend in men, but a sharply increasing trend in women, seen in Netherlands, Poland and Switzerland. The period effects（SCC） for males and females from the APC model applied to the data from the 19 countries: an increasing trend in both sexes, seen in Taiwan and Estonia; an decreasing trend in both sexes, seen in Singapore, USA, England and Wales, Netherland, Switzerland, Japan, India, Israel, France, Denmark, Italy and Australia; a sharply increasing trend in both sex, seen only in Spain; a sharply decreasing trend in women, but a increasing trend in men, seen only in Iceland; a relatively steady trend in men, but a gradually increasing trend in women seen in Slovakia and Poland. Conclusions: The sex ratio of the ASIR for adenocarcinoma（AC） was lower than sex ratio of the ASIR for squamous cell crcinoma（SCC） in 19 countries. These trends may reflect that SCC related with sex difference more than AC. A period effect（AC） was increasing in both sex seen in most countries, especially in Taiwan and Asia countries. But a period effect（SCC） decreasing in both sex seen in most countries（Singapore, North America and Europe countries）. A period effect（SCC） was increasing in both sex seen in Taiwan.