| Summary: | 碩士 === 嘉南藥理科技大學 === 化妝品科技研究所 === 98 === The quantity and intensity of UV that reaches the surface have increased, because the hole of ozone layer was gradually expanded. Since UV cause melanism, photoaging, and skin cancer to the human skin, it is important that using sunscreen products protects yourself. The chemical type of sunscreen composition might be degenerated to lose the ability by sun light. Therefore, the study was on the sunscreen effect by adding antioxidant activity of natural products.and UV absorption activity of Chinese herbal medicines.
The application of natural product as a component of the cosmetic product is a trend at present in the cosmetic industry, because the orientations conform the consumer demands for health, natural, low-hazard demand. In this study, the natural products are jaboticaba, lotus, and houseleek. The extraction of the natural products were researched the effect of antioxidant, whitening, cytotoxicity, etc.. Then, the extraction added to the sunscreen, and assessed the sunscreen effect. In addition, UV absorption activity of Chinese herbal medicines which were Terminalia catappa L. leaf, Nelumbo nucifera G. leaf, Cuscuta chinensis Lam. seed, Paeonia suffruticosa Andr. root bark added to the sunscreen, and assessed the sunscreen effect. By this way, we could investigate the extraction of natural products using in sunscreen.
The results showed that the extraction of lotus outer membrane showed the minimum scavenge concentration in DPPH radical assay (SC50: 0.0047 mg/mL); the extraction of jaboticaba seed showed the highest-level value in trolox equivalent antioxidant capacity assay(6215 μmol of Trolox/g); the extraction of jaboticaba seed showed the most effective of protection pUC 119 DNA, and the extraction of jaboticaba stem showed the most effective of protection λ/HindⅢ DNA; in total phenol content assay, the extractions of lotus outer membrane and jaboticaba seed were the highest-level value(520 mg of GAE/g, 507 mg of GAE/g); the extractions of jaboticaba seed, fresh lotus fruit, and lotus outer membrane had slightly toxic when the concentration is higher than 0.1 mg/mL, applications need more attention.
The results of sunscreen effect showed that the extraction of natural products could promote the absorbance of Parsol MCX solution at 310 nm, and the extraction of NN-SM was the most effective (promotion 0.500); the portion extraction of natural products could promote the absorbance of Parsol 1789 solution at 348 nm and 361nm, but the effect was lower than Parsol MCX. In SPF assay, sunscreen added antioxidant activity of natural products could promote SPF. In addition, UV absorption activity of Chinese herbal medicines added to the sunscreen, and assessed the sunscreen effect. Based on the above, the extractions of natural products have the potential to develop as a cosmetic raw material
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