| Summary: | 碩士 === 國立陽明大學 === 護理學系暨研究所 === 97 === The purpose of this study was to explore the relationship between the symptoms distress and the quality of life in patients with End-Stage Renal Disease before and after parathyroidectomy. A descriptive and correlation study design was undertaken. Thirty-seven participants were recruited from a medical center over two years of period. Data was analyzed by using descriptive statistics, pair t-test and pearson，s correlation.
The result reveals that joint pain, muscle weakness and itchy skin were the most annoying symptoms and the total scores of PCS was 31.7± 13.8,MCS 37.6±14.4 respectively. There were 86.5% of patients indicated experiencing adverse symptoms and as the result affecting their quality of life. However, the symptoms improved after parathyroidectomy. Among these cases, there was a noticeable negative correlation between the level of serum calcium and PCS and MCS; in contrast, a positive correlation between the calcium-phosphorus product and skin itching was observed. Preoperative serum albumin was related to PCS (r=0.354, p=0.047). In addition, after three months of operation there was a significant correlation between the serum albumin level and PCS (r= 0.374, p=0.035) and MCS (r=0.416,p=0.018). Joint pain, muscle weakness, and skin itching have alleviated greatly both at one month and three months of time after parathyroidectomy. The result of this research can facilitate nursing staff to understand the pre-operative symptoms distress and the necessity in patients with ESRD and parathyroidism; and provide them with individually appropriate care to better their quality of life.
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