Topoisomerase I inhibition mediates evodiamine cytotoxicity on cancer cells

碩士 === 臺北醫學大學 === 醫學科學研究所 === 97 === The regulation of DNA relaxation by Topo I is essential for DNA replication, transcription, and recombination events. Topo I activity is elevated in various cancer cells, thus Topo I has been identified as an important therapeutic target in cancer chemotherapy. C...

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Bibliographic Details
Main Authors: Hui-Yuan Lin, 林惠元
Other Authors: Chun-Mao Lin
Format: Others
Language:zh-TW
Published: 2009
Online Access:http://ndltd.ncl.edu.tw/handle/89890632013174065401