The relationship among various definitions of pressor reactivity, baroreceptor sensitivity, ambulatory blood pressure and subjective perception of the stress tasks

• Main Authors: Yu-Lin Wu, 吳宥霖
• Other Authors: Pei-Shan Tsai
• Format: Others
• Language: zh-TW
• Published: 2009
• Online Access: http://ndltd.ncl.edu.tw/handle/22860652236556824355

碩士 === 臺北醫學大學 === 護理學研究所 === 97 === The purpose of this study was to examine the relationship among various definitions of pressor reactivity, baroreceptor sensitivity (BRS), ambulatory blood pressure and subjective perception of the stress tasks Methods: This study included 56 subjects with prehypertension and stage 1 hypertensives. Blood pressure reactivity to the stress tasks were measured using a noninvasive hemodynamic monitoring system (Finometer, FMS, Netherlands) continuously throughout the whole stress session. Then to calculate blood pressure reactivity (BPR) by various definitions, such as maximum BPR, average BPR, area under the curve and blood pressure recovery. And using the software (PRVBRS) to analysis BRS. The Ambulatory BP measurement was performed over a 24-hour period using an automatic BP recorder (Model 90217, SpaceLabsTM Inc., Redmond, WA, USA). The major findings of this study were as followed: 1) After controlling age, clinical heart rate and body mass index, the inferior BRS with elevated average and area under the curve (AUC) systolic blood pressure (SBP) reactivity (r = -0.34, r = -0.29; p = .01, p = .04) and diatonic blood pressure (DBP) reactivity (r = -0.38, r = -0.31; p = <.01, p = .02). 2) The subjects were tired during the stress tasks and the AUC SBP reactivity decrease (r = -0.33; p = .017). The subjects do efforts, the SBP recover poorly (r = 0.28; p = .044). 3) The subjects with higher maximum SBP reactivity and the standard deviation (SD) of SBP and DBP to 24 hours in daily life were smaller (r = -0.32, r = -0.01; p = .02, p = .01)。 The conclusions of this study was in prehypertension and stage 1 hypertensives, exaggerated blood pressure reactivity in average and AUC definitions was related with inferior BRS. Subjective perceptions of the stress tasks affect blood pressure reactivity. These results are basis knowledge to understand the mechanism of blood pressure reactivity and select the pressor tasks.