| Summary: | 碩士 === 亞洲大學 === 保健營養生技學系碩士班 === 97 === Emilia sonchifolia (L.) DC. (Lilac tasselflower, yi dian hong, Asteraceae) is used in folk medicine as antipyretic and a remedy against influenza. In this study, we have investigated the hepatotoxic and tumorigenic pyrrolizidine alkaloids (PAs) contained in Emilia sonchifolia (L.) DC. collected from several towns in Taiwan. Two structural types of PAs were identified from the ground whole plant by Gas Chromatography-Mass Spectrometry method: (1) retronecine bases, e.g. senecionine (1) seneciphylline (2) and integerrimine (3); (2) otonecine bases, e.g. senkirkine (4), otosenine (5), neosenkirkine(6), petasitenine (7), acetyl senkirkine (8), desacetyldoronine (9) acetyl petasitenine (10), and doronine (11). Quantitation of the individual PA was determined by linear regression curves. The methyl stearate (27) in two concentration ranges, 8-125 μg/mL and 100-1000 μg/mL, was examined as an internal standard. Senkirkine figured as a major PA (303.5~1131.3 μg/g) in Emilia sonchifolia. (L.) DC. This study will provide important information to public consumers regarding the health risk of intake Emilia sonchifolia (L.) DC. containing PAs.
|
|---|
