| Summary: | 碩士 === 大仁科技大學 === 製藥科技研究所 === 97 === Yam (Dioscorea species), a member of the monocotyledonous family Dioscoreaceae, has frequently been used as Chinese herbal medicines. Two Chinese yams, D. alata L. cv. Tainong No. 1 (TN1) and D. alata L. cv. Tainong No.2 (TN2) are harvested in Taiwan. In this study, the market for the common yam in Taiwan TN1 and TN2, tubers, respectively, after the separation of their skin, with water extraction. Also two yam tubers were succulent and the rice bran and to speculation terra frava usta land speculation concocted a way to carry out. Before and after the processing of water yam extract for total phenolics and flavonoids Determination and assessment of these water extracts of α, α-diphenyl-β-picryhydrazyl (DPPH) radical scavenging effect.
In addition, mice with enough to reverse the swelling test and acetic acid test or the test wound healing in rats, as well as tyrosinase and inhibition of melanoma cells (B16-F10 murine melanoma cells) derived from cytotoxicity tests results to assess the cooked meat in Taiwan yam tubers and its biological activity of skin differences.
The experimental results confirmed this speculation and land speculation rics bran and terra frava usta yam tubers after the skin can improve the removal of DPPH free radical, anti-inflammatory, analgesic, as well as the formation of inhibitory activity of melanoma, especially on the rice bran yam tuber skin to enhance the activity of a more significant , but not with melanoma cells, the effects of poisoning.This role may be related to water extraction can improve the processing yam tuber skin active ingredient, that is, the total phenolics content of the precipitation, but the content of flavonoids does not have an impact. Will be rice bran TN2 skin made of the water extract ointment and found that early trauma can promote the transforming growth factor (transforming growth factor-β) expression, which constitutes a cell to extracellular matrix (extracellular matrix)-related proteins such as collagen and fibronectin increased performance, contribute to wound healing. In addition, on the rice bran TN2 yam root extract water jacket for the rabbits there is no skin irritation and eye irritation role. The results of this experiment can be used as for the pharmaceutical and cosmetics industries yam future technologies related to the development of reference preparations.
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