A Two-Dimensional Mathematical Model Simulating Intracellular Diffusion Quantifies Contributions of Steric Hindrance and Binding Effect

A Two-Dimensional Mathematical Model Simulating Intracellular Diffusion Quantifies Contributions of Steric Hindrance and Binding Effect

碩士 === 國立中興大學 === 化學工程學系所 === 97 === Intracellular mass transport plays as critical role in biological function, a variety of genetic diseases are related to the mal function of intracellular transport. Previous research on quantification of cytoplasmic diffusion coefficient has isolated the binding...

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Main Authors: Che-Ting Kuo, 郭哲庭
Other Authors: 張厚謙
Format: Others
Language:zh-TW
Online Access:http://ndltd.ncl.edu.tw/handle/64615808954050433817
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spelling ndltd-TW-097NCHU50630052016-04-29T04:19:41Z http://ndltd.ncl.edu.tw/handle/64615808954050433817 A Two-Dimensional Mathematical Model Simulating Intracellular Diffusion Quantifies Contributions of Steric Hindrance and Binding Effect 以二維數值模型模擬細胞的擴散及調整空間立體障礙效應與結合機制 Che-Ting Kuo 郭哲庭 碩士 國立中興大學 化學工程學系所 97 Intracellular mass transport plays as critical role in biological function, a variety of genetic diseases are related to the mal function of intracellular transport. Previous research on quantification of cytoplasmic diffusion coefficient has isolated the binding effect as one of the factor in determination of apparent diffusion coefficient. This research further isolated steric hindrance from factor such a viscosity and binding .Contribution of retarder from diffusion obstacle such as cytoskeleton and organelles are calculated and quantified. Results of the mathematical model are compared with experimental data from literature and satisfactory agreements are obtained. 張厚謙 學位論文 ; thesis 90 zh-TW
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language zh-TW
format Others
sources NDLTD
description 碩士 === 國立中興大學 === 化學工程學系所 === 97 === Intracellular mass transport plays as critical role in biological function, a variety of genetic diseases are related to the mal function of intracellular transport. Previous research on quantification of cytoplasmic diffusion coefficient has isolated the binding effect as one of the factor in determination of apparent diffusion coefficient. This research further isolated steric hindrance from factor such a viscosity and binding .Contribution of retarder from diffusion obstacle such as cytoskeleton and organelles are calculated and quantified. Results of the mathematical model are compared with experimental data from literature and satisfactory agreements are obtained.
author2 張厚謙
author_facet 張厚謙
Che-Ting Kuo
郭哲庭
author Che-Ting Kuo
郭哲庭
spellingShingle Che-Ting Kuo
郭哲庭
A Two-Dimensional Mathematical Model Simulating Intracellular Diffusion Quantifies Contributions of Steric Hindrance and Binding Effect
author_sort Che-Ting Kuo
title A Two-Dimensional Mathematical Model Simulating Intracellular Diffusion Quantifies Contributions of Steric Hindrance and Binding Effect
title_short A Two-Dimensional Mathematical Model Simulating Intracellular Diffusion Quantifies Contributions of Steric Hindrance and Binding Effect
title_full A Two-Dimensional Mathematical Model Simulating Intracellular Diffusion Quantifies Contributions of Steric Hindrance and Binding Effect
title_fullStr A Two-Dimensional Mathematical Model Simulating Intracellular Diffusion Quantifies Contributions of Steric Hindrance and Binding Effect
title_full_unstemmed A Two-Dimensional Mathematical Model Simulating Intracellular Diffusion Quantifies Contributions of Steric Hindrance and Binding Effect
title_sort two-dimensional mathematical model simulating intracellular diffusion quantifies contributions of steric hindrance and binding effect
url http://ndltd.ncl.edu.tw/handle/64615808954050433817
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