Preparation of Quaternary Ammonium Group Functionalized Magnetic Nanoparticles

• Main Authors: Pei-Chuan Hsieh, 謝佩娟
• Other Authors: Shu-Jen Chen
• Format: Others
• Language: zh-TW
• Published: 2009
• Online Access: http://ndltd.ncl.edu.tw/handle/30618559423524379507

碩士 === 國立高雄應用科技大學 === 化學工程與材料工程系 === 97 === Two different types of novel quaternary ammonium functionalized magnetic nanoparticles were synthesized in this study. The magnetic nanoparticles were first prepared by co-precipitation of ferrous and ferric iron electrolytic solutions, followed by hydrolyzing tetraethylorthosilicate (TEOS) in mild alkaline condition. Transmission electron micrographs showed that the nanoparticles of iron oxide with the size ranging from 5 to 10 nm were dispersed in amorphous silica. The surface of magnetic silica was first modified by grafting the magnetic nanoparticles with glycidyltrimethylammonium chloride (GAC). The second modification method was performed by grafting with aminopropyltriethoxysilane (APTS) followed by quaternarization of nitrogen with various alkyl halides. It was found that the nanoparticles grafted with GAC showed high affinity to hyaluronic acid (HA). The HA adsorption capacity of GAC-grafted magnetic silica nanoparticles was 0.028 g/g support, indicating that the GAC-grafted nanoparticles is a good absorbent for recovering anion biopolymers.