Antioxidant Constituents of Rhus javanica var. roxburghiana

• Main Authors: Jen-Chieh Yang, 楊仁傑
• Other Authors: Chung-Nan Lin
• Format: Others
• Language: zh-TW
• Published: 2009
• Online Access: http://ndltd.ncl.edu.tw/handle/95678689426158006719

碩士 === 高雄醫學大學 === 藥學研究所 === 97 === The extract obtained from the fruit of Rhus javanice L. var. roxburghiana was performed several biological studies associated with free radical, including DPPH,ABTS, and xanthine oxidase inhibitory assays. Among these studies, the extract exhibited significantly inhibitory effect on production of free radicals. In this study, kaempferol (5) was first isolated from fruit of Rhus javanice L. var. roxburghiana. On the other way, four compounds, taxifolin (1) ,2,3-cis-3,4- trans-7,4’-dihydroxy- flavan-3β,4β-diol (2) , fustin (3), 7,3’,4’-trihydroxy-flavone (4), previously isolated, from the stem of this plant were performed DPPH, ABTS, and xanthine oxidase assays. Compounds (1), (2) and (3) showed significantly inhibitory activity. As these result shown, taxifolin (1) was found as a potent xanthine oxidase inhibitor. Based on chemotaxonomic theory, the above four compounds (1)-(4) may be also appears in the extract of fruit of this plant.