Role of ATM/ATR-p53-p21WAF1 signaling pathway in Arecoline-induced DNA damage and cytotoxicity in Clone-9 cells

博士 === 高雄醫學大學 === 醫學研究所 === 97 === Betel quid chewing is a risk factor of liver cirrhosis and hepatocellular carcinoma, especially in Taiwan. However, the pathogenic mechanism remains unclear. Arecoline is the most abundant alkaloid in betel quid and is cytotoxic, genotoxic, mutagenic and tumorigeni...

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Bibliographic Details
Main Authors: Wen-Wen Chou, 周玟玟
Other Authors: Lea-Yea Chuang
Format: Others
Language:zh-TW
Published: 2009
Online Access:http://ndltd.ncl.edu.tw/handle/50804802064595775954