The study of the relationship between the human pulp stone and the cardiovascular diseases

• Main Authors: Ku-Ming Chen, 陳谷銘
• Other Authors: Chun-Zheng Hong
• Format: Others
• Language: zh-TW
• Published: 2009
• Online Access: http://ndltd.ncl.edu.tw/handle/43839852827748790580

碩士 === 高雄醫學大學 === 牙醫學研究所 === 97 === Objective: The mechanism of the formation of the pulp stone has not been found out totally. The previous study indicates that some systemic diseases or syndromes (ex: osteitis deformans、acromegaly and atherosclerosis ) are associated with pulp stone prevalence. Cardiovascular diseases have been the top ten cause of death for many years in Taiwan. In the present study, we classify the risk of the cardiovascular diseases according to measuring the intima-media thickness (IMT) of the bilateral common carotid artery and investigate the prevalence of the pulp stone, the square measure of the pulp stone in the molar and the pulp stone / teeth number ratio. The aim of this study is to correlate the relationship between the risk factor of the cardiovascular diseases and the three indexes of the pulp stone. We expect that the indexes of the pulp stone can project the risk of the cardiovascular diseases through this study. Material and Methods: 77 patients that have the complaints of chest pain or other symptoms are from cardiology department of the in KMU hospital (male: female=54:23). We use carotid artery ultrasound to get the IMT of the common carotid artery and diagnose metabolic syndrome according to the laboratory data of the patients. The three index of the pulp stone (the prevalence of the pulp stone, the square measure of the pulp stone in the molar and the pulp stone / teeth number ratio) are measured by radiographic method with periapical films. The results are analyzed by student t-text, chi-square test, multiple regression and logistic regression to compare the indexes of the pulp stone in the patients with different IMT and metabolic syndrome. Result: The pulp stone / teeth ratio and the pulp stone / molar teeth ratio are marginally significantly higher in the patients with higher IMT (p=0.0548, p=0.0525), but no significant difference among the patient with different sex, age and metabolic syndrome. The square measure of the pulp stone in the molar is no significant difference among different sex, age, IMT and metabolic syndrome. The prevalence is significantly higher in the patients with higher IMT (≧0.985mm) (p=0.0250) and marginally significantly higher in the older patient.(p=0.0505) Conclusion: The age and the intima-media thickness of the bilateral common carotid artery may be the effective factor of the formation of the pulp stone. The patients with the higher possibility of the calcified artery have the higher pulp stone prevalence, the pulp stone / teeth ratio and the pulp stone / molar teeth ratio. According to this result, the formation of the pulp stone may be associated with the atherosclerosis.