Drug Release using Magnetic Hollow Spheres and Nanotubes

碩士 === 中原大學 === 奈米科技碩士學位學程 === 97 === This study explores how to synthesize Fe3O4 magnetic nanoparticles by the chemical coprecipitation method and their applications in drug release. Fe3O4 hollow nanoparticles and Fe3O4 nanotubes were synthesized by various surfactants and templates, while Fe3O4/Si...

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Bibliographic Details
Main Authors: Tz-Jang Chen, 陳梓彰
Other Authors: Hong-Wen Wang
Format: Others
Language:zh-TW
Published: 2009
Online Access:http://ndltd.ncl.edu.tw/handle/89595616750997374446
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Summary:碩士 === 中原大學 === 奈米科技碩士學位學程 === 97 === This study explores how to synthesize Fe3O4 magnetic nanoparticles by the chemical coprecipitation method and their applications in drug release. Fe3O4 hollow nanoparticles and Fe3O4 nanotubes were synthesized by various surfactants and templates, while Fe3O4/SiO2 core-shell spheres were made by Stober process. The Fe3O4 hollow spheres and nanotubes have the advantages of superparamagneticity, low loxicity and is applicable to drug release. Fe3O4/SiO2 is successfully synthesized by using different surfactants in the sol-gel process.Their pore size on the porous particles is around 2-4nm. In this study, Fe3O4 nanotubes sensitivity were higher than Fe3O4 nanowires by testing in cyclic voltammetry (CV). The drug release characteristics for Fe3O4 hollow spheres, Fe3O4 nanotubes and the Fe3O4/SiO2 spheres were demonstrated.