The investigation of object concept in patients with Parkinson''s disease

碩士 === 中國醫藥大學 === 神經科學與認知科學研究所 === 97 === Concept is the basic element that helps us to understand the language of hought. Different object semantic attributes was described to object concept. Concepts includes visual and functional features. The similar concepts may be represented in similar ways....

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Bibliographic Details
Main Authors: Wei-Chi Lin, 林瑋琪
Other Authors: 許儷絹
Format: Others
Language:zh-TW
Published: 2009
Online Access:http://ndltd.ncl.edu.tw/handle/94197334243691744841
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Summary:碩士 === 中國醫藥大學 === 神經科學與認知科學研究所 === 97 === Concept is the basic element that helps us to understand the language of hought. Different object semantic attributes was described to object concept. Concepts includes visual and functional features. The similar concepts may be represented in similar ways. Parkinson’s disease (PD) is a neurodegeneration disease that caused by neural loss in substantia nigra, leading to the neurotransmitter, dopamine, decreases in the mid brain. Previous studies found that PD patients have deficits in identifying animate objects ( Antal, et al., 2002 ; Righi, et al., 2007). It was also found that PD patients have deficits in naming actions (Cotelli, et al., 2007). Since most animate objects are movable and most inanimate objects are unmovable, the main purpose here is to investigate whether PD’s deficit in categorizing animate or inanimate objects would confound with the movable/unmovable variable. We use the object decision task in which participants have to decide whether pictures represented real objects or non-objects.. It was a 2 (animate and inanimate) x2 (moveable and unmovable) experimental design. The reaction time and correct rate were both recorded and a repeated-measures ANOVA analysis was adopted. Preliminary results showed that :(1)The reaction time of processing animate objects in PD was slower than that of processing inanimate ones.;(2) The reaction time of processing movable objects in PD was also slower than that of processing unmovable ones. (3) There is interaction between animate/inanimate and movable/unmovable variables. We can conclude that PD patients have deficit in categorizing animate or inanimate objects,the moveable variable may be the influence factor.