Associations between thymidylate synthase polymorphisms and survival in colorectal cancer patients treated with 5-FU-based adjuvant chemotherapy
碩士 === 中國醫藥大學 === 環境醫學研究所碩士班 === 97 === 5-fluorouracil (5-FU) is one of the mainstays of standard anti-cancer drugs used in the chemotherapy for colorectal cancer (CRC). It inhibits thymidylate synthase (TS) by forming a covalent ternary complex with 5-fluorodeoxyuridylate (FdUMP) and results impair...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Others |
| Language: | zh-TW |
| Published: |
2009
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| Online Access: | http://ndltd.ncl.edu.tw/handle/84525724760442319321 |