RCR vector-mediated suicide genes of cytosine deaminase and thymidine kinase therapy for breast cancer by local activation of prodrugs
碩士 === 國立中正大學 === 分子生物研究所 === 97 === Gene-directed enzyme prodrug therapy (GDEPT) is a widely used approach to increase drug selectivity for cancer therapy. However, a single prodrug-activated system often does not induce complete tumor regression or avoid tumor recurrence after termination of prodr...
Main Authors: | Yi-ping Luo, 羅怡屏 |
---|---|
Other Authors: | Chien-Kuo Tai |
Format: | Others |
Language: | en_US |
Published: |
2009
|
Online Access: | http://ndltd.ncl.edu.tw/handle/51424468316036381640 |
Similar Items
-
Imaging Expression of Cytosine Deaminase-Herpes Virus Thymidine Kinase Fusion Gene (CD/TK) Expression with [I]FIAU and PET
by: Trevor Hackman, et al.
Published: (2002-01-01) -
The crystal structure of yeast cytosine deaminase and its application in enzyme-prodrug gene therapy.
by: Yi-Hsin Hsu, et al.
Published: (2003) -
Characteristics and efficacy of cytosine and cytidine deaminase
by: Qusay Chalabi, et al.
Published: (2007-01-01) -
Research advances on cytosine deaminase APOBEC1
by: ZHOU Binghan, et al.
Published: (2020-04-01) -
CRISPR-mediated base editing in mice using cytosine deaminase base editor 4
by: Salah Adlat, et al.
Published: (2021-07-01)