| Summary: | 碩士 === 國立陽明大學 === 醫學工程研究所 === 96 === Abstract
Purpose:
Initial fixation strength is critical for the early post-operative rehabilitation of patients with anterior cruciate ligament (ACL) reconstructions. However, even the best femoral fixation devices remain controversial. We compared the biomechanical characteristics of tendon grafts fixed by different biodegradable femoral fixation devices following ACL reconstruction.
Methods:
The Bio-TransFix, Rigidfix, Bioscrew with EndoPearl augmentation and Bioscrew devices were used to fix porcine flexor digitorum profundus tendon grafts in 32 porcine femora. Displacement of each tendon graft was evaluated after cyclic loading testing. Stiffness, ultimate failure load and failure mode of these fixation devices were measured with load-to-failure testing.
Results:
The displacement of the femur-graft-cement complex in response to cyclic loading was lower (P < 0.05) for the Bio-TransFix than the Rigidfix, Bioscrew with EndoPearl augmentation, and Bioscrew groups. The fixation stiffness values of the Rigidfix and the Bioscrew were significantly greater (P < 0.05) than that of the Bio-TransFix, but not significantly different from that of the Bioscrew with EndoPearl augmentation. The ultimate failure load was significantly greater for the Bio-TransFix and the Rigidfix than the Bioscrew with EndoPearl augmentation or the Bioscrew (P < 0.05).
IV
Conclusions:
The Bio-TransFix provided the least graft displacement under cyclic loading. However, this device gave less stability. The Rigidfix device provided better stability and stiffness of the tendon graft among those fixation devices that showed no significant differences in graft displacement under cyclic loading.
Clinical Relevance:
Secure graft fixation is a prerequisite for accelerated rehabilitation programs following ACL reconstruction before bony incorporation of the graft. However, no single fixation device provided less displacement along with a larger failure load and stiffness in this study.
Keyword: Biomechanics, Biodegradable device, Tendon graft, Anterior cruciate ligament reconstruction.
|
|---|
