The Reaction and Spectroscopic Study between Substituted benzaldehyde oxime and N-Chlorosuccinimide

• Main Authors: Cheng-yen Su, 蘇正晏
• Other Authors: Shaw-tao Lin
• Format: Others
• Language: zh-TW
• Published: 2008
• Online Access: http://ndltd.ncl.edu.tw/handle/92028691991183251411

碩士 === 靜宜大學 === 應用化學研究所 === 96 === A series of substituted benzaldehyde oximes were prepared via the condensation reactions between substituted benzaldehyde and hydroxylamine hydrochloride in the room temperature. Upon the treatment of those substituted benzaldehyde oximes with N-chlorosuccinimide under base conditions to proceed cycloadditional reactions, that obtained a series of aryloxazirines. All of the new compounds have been confirmed as compared with others isomers CHNO by MS, NMR , analysis. In the 1H NMR of aryloxazirine, Only the benzene ring have the absorb signal of prontons. The chemical shifts of C7 appear at 140 ppm when the substituted group can afford electrons; whereas, the chemical shifts of C7 appear at 138 ppm when the substituted group can accept electrons. Additionally, aryloxazirine was esaily to producted when the substituted group can afford electrons, and use GC spectrogram to calculate dimension that product around 80%. Moreover, we control the reaction condition in cold temperature and abound with nitrogen, it will reduce more impurities to producting.