Synthesis of Novel Pt-Complexes as Anti-Cancer Prodrugs with DNA-Cleaving Ability

碩士 === 國立清華大學 === 化學系 === 96 === A synthetic pathway of new organoplatinum complex as anti-cancer prodrugs with DNA-cleaving ability was developed. On the other hand, we investigated the single-strand scission of phiX 174 RFI DNA by irradiated platinum complexes with UV light. Furthermore, the pla...

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Main Authors: Jr-Yuan Lu, 盧致遠
Other Authors: Jih-Ru Hwu
Format: Others
Language:en_US
Published: 2008
Online Access:http://ndltd.ncl.edu.tw/handle/44016918929921146186
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spelling ndltd-TW-096NTHU50651152015-11-27T04:04:17Z http://ndltd.ncl.edu.tw/handle/44016918929921146186 Synthesis of Novel Pt-Complexes as Anti-Cancer Prodrugs with DNA-Cleaving Ability 合成新鉑錯化物作為具DNA切割能力之抗癌前驅藥物 Jr-Yuan Lu 盧致遠 碩士 國立清華大學 化學系 96 A synthetic pathway of new organoplatinum complex as anti-cancer prodrugs with DNA-cleaving ability was developed. On the other hand, we investigated the single-strand scission of phiX 174 RFI DNA by irradiated platinum complexes with UV light. Furthermore, the platinum complex 10 with carboxylic acid was expected for more study in the future. Jih-Ru Hwu 胡紀如 2008 學位論文 ; thesis 35 en_US
collection NDLTD
language en_US
format Others
sources NDLTD
description 碩士 === 國立清華大學 === 化學系 === 96 === A synthetic pathway of new organoplatinum complex as anti-cancer prodrugs with DNA-cleaving ability was developed. On the other hand, we investigated the single-strand scission of phiX 174 RFI DNA by irradiated platinum complexes with UV light. Furthermore, the platinum complex 10 with carboxylic acid was expected for more study in the future.
author2 Jih-Ru Hwu
author_facet Jih-Ru Hwu
Jr-Yuan Lu
盧致遠
author Jr-Yuan Lu
盧致遠
spellingShingle Jr-Yuan Lu
盧致遠
Synthesis of Novel Pt-Complexes as Anti-Cancer Prodrugs with DNA-Cleaving Ability
author_sort Jr-Yuan Lu
title Synthesis of Novel Pt-Complexes as Anti-Cancer Prodrugs with DNA-Cleaving Ability
title_short Synthesis of Novel Pt-Complexes as Anti-Cancer Prodrugs with DNA-Cleaving Ability
title_full Synthesis of Novel Pt-Complexes as Anti-Cancer Prodrugs with DNA-Cleaving Ability
title_fullStr Synthesis of Novel Pt-Complexes as Anti-Cancer Prodrugs with DNA-Cleaving Ability
title_full_unstemmed Synthesis of Novel Pt-Complexes as Anti-Cancer Prodrugs with DNA-Cleaving Ability
title_sort synthesis of novel pt-complexes as anti-cancer prodrugs with dna-cleaving ability
publishDate 2008
url http://ndltd.ncl.edu.tw/handle/44016918929921146186
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