Synthesis of Novel Pt-Complexes as Anti-Cancer Prodrugs with DNA-Cleaving Ability
碩士 === 國立清華大學 === 化學系 === 96 === A synthetic pathway of new organoplatinum complex as anti-cancer prodrugs with DNA-cleaving ability was developed. On the other hand, we investigated the single-strand scission of phiX 174 RFI DNA by irradiated platinum complexes with UV light. Furthermore, the pla...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Others |
| Language: | en_US |
| Published: |
2008
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| Online Access: | http://ndltd.ncl.edu.tw/handle/44016918929921146186 |
| Summary: | 碩士 === 國立清華大學 === 化學系 === 96 === A synthetic pathway of new organoplatinum complex as anti-cancer prodrugs with DNA-cleaving ability was developed. On the other hand, we investigated the single-strand scission of phiX 174 RFI DNA by irradiated platinum complexes with UV light. Furthermore, the platinum complex 10 with carboxylic acid was expected for more study in the future.
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