Analysis of an over-expressed protein induced by serum-deprivation stress on oral cancer cells

碩士 === 國防醫學院 === 牙醫科學研究所 === 97 === Using serum deprivation as a stress stimulation to explore OECM-1 cells survival and tumorigenic mechanisms for tumor growth by using two-dimensional gel electrophoresis in combination with mass spectrometry. We found out 10 over-expressed spots in this experiment...

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Bibliographic Details
Main Authors: Ya-Sheng, Chang, 張雅勝
Other Authors: Jenn-Han, Chen
Format: Others
Language:zh-TW
Published: 2008
Online Access:http://ndltd.ncl.edu.tw/handle/80700410173452815205
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Summary:碩士 === 國防醫學院 === 牙醫科學研究所 === 97 === Using serum deprivation as a stress stimulation to explore OECM-1 cells survival and tumorigenic mechanisms for tumor growth by using two-dimensional gel electrophoresis in combination with mass spectrometry. We found out 10 over-expressed spots in this experiment. We analysis these proteins by mass spectrometry and we found out one of these proteins named COG-4, that is required for normal Golgi morphology and function. It plays an important role in Golgi protection and stability.