Development of 3D tool with Multidetector Row Computed Tomography for analysing LV function

• Main Authors: Jo-ying Hsueh, 薛若盈
• Other Authors: Hu Wei-chih
• Format: Others
• Language: zh-TW
• Published: 2008
• Online Access: http://ndltd.ncl.edu.tw/handle/83206187851187820074

碩士 === 中原大學 === 醫學工程研究所 === 96 === The purpose of this study is to observe the significant differences on the shape and motion of the heart between health heart and heart with coronary artery disease or the dysfunction non-invasively. We will be using the parameters of the left ventricle reconstructed from cardio CT images to analyze ventricular functions. The parameters were volume-time curve (VTC), ejection fraction (EF), peak ejection rate (PER), peak filling rate (PFR), wall motion (WM), and wall thickness (WT). To delineate and integrate LV contour, first, we have constructed the 3D cardiac model that was used for the separation of left ventricle from the aorta and mitral valve. Second, the seed region growth algorithm was used to delineate both endocardial and epicardial contour slice by slice. This study has researched into the correlation between the above-mentioned parameter and the EF values. The subjects include seven patients with suspected AF, and the other five patients with mitral valve problem. The results showed that correlation between stroke volume and EF was 0.89 (r=0.89). The correlation between the rate change from PER to PFR and EF was 0.88(r=0.88). The correlation between quantity of wall motion and EF was 0.92 (r=0.92).The correlation between quantity of wall thickness and EF was 0.8 (r=0.8). According to the results, it is useful for evaluating the function of left ventricle.