| Summary: | 碩士 === 嘉南藥理科技大學 === 營養與保健科技研究所 === 96 === Diabetes and obesity are known to increase the risk of cardiovascular disease (CVD). The American Diabetes Association (ADA) has suggested that type 2 diabetes need to control their glycemia, lipid and blood pressure to prevent of cardiovascular diseases. The present study aimed to conduct a systematic evaluation on the effects of weight changes on glycemia, lipid and blood pressure in patients with type 2 diabetes. From 2004 to 2006, convenience sampling method was used to screen for overweight or obese patients with type 2 diabetes. Patients accepted for the study were traced for a year to observe for weight changes and then categorized into two groups; group one was those achieved body weight loss group two having no change or increase in weight. Differences in these measurements within and between groups were compared based on recommended by ADA in 2006, i.e. HbA1c < 7.0 %, TG < 150 mg/dl, LDL < 100 mg/dl, HDL > 35 mg/dl and blood pressure < 130/80 mmHg. Results showed that fasting blood sugar , HbA1c, TG, cholesterol and BP were noted to decrease but were not different between the two groups. However, body weight loss subjects tend to achieve ADA currently recommended goals of prevention CVD more than body weight gain subjects. These results suggest that diabetes patients with intention to complete the diabetes shared care model, whether body weight increase or decrease, were effective in blood glucose, lipid and pressure, with more from weight loss group than the weight gain group in achieving the ADA recommended goals. This study suggests that modest weight loss can have a long-time impact on prevention CVD risk.
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