| Summary: | 碩士 === 長庚大學 === 醫療機電工程研究所 === 96 === The middle ear cavity is a space full of air. There are three ossicles in this space: the malleus, the incus and the stapes. The ossicles connect the tympanic membrane and the inner ear. The sound wave would be enlarged and conducted into inner ear by the ossicles, and then the sound wave would be transformed into auditory evoked potential by inner ear for human to hear sounds. Clinically, the ossicles would be affected and would result in conductive hearing loss due to the ossicular congenital anomalies or fracture, chronic suppurative otitis media and cholesteatoma. To understand the influence of the middle ear diseases on the ossicular vibration, the finite element analysis was utilized in previous study. The 3D model of ossicles was reconstructed by cadaver histology section or computed tomography scan. However, the influence of singular point upon the 3D model of in-vivo human ossicles was lack of discussion. Therefore, this study would discuss the optimization analysis for the geometry of ossicles and smoothing method, and then the lengths of the geometry of ossicles would be measured.
Antibiotics were mostly used to cure CSOM. As otorrhea became serious complication, tympanoplasty was mostly performed to control the infection. Contraindications to tympanoplasty would vary from one surgeon to another depending upon his training, philosophy, experience, and surgical skill. The geometry of tympanic membrane would be changed due to tympanoplasty. Nevertheless, the discussion of the curvature of in-vivo human tympanic membrane was still short of. Hence, this study would non-invasively measure the geometry and the 2D curvature of in-vivo human tympanic membrane.
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