| Summary: | 碩士 === 長庚大學 === 醫務管理學研究所 === 96 === Objectives: This was a prime study in trends in neonatal morbidity and mortality for low birth weight preterm infants.
Methods: We included infants who were born between 1996 and 2005 with birth weight 500-2500g and admitted to the neonatal intensive care unit in Chang-Gung Children’s Hospital.
Results: A total of 5065 low birth weight preterm infants were enrolled in this study. Mortality decreased from 12.09% in 1996 to 4.39% in 2005. In particular, the mortality of extremely low birth weight (<1000g) infants decreased significantly. The independent risk factors of mortality were low gestational age, low birth weight, Apgar score at l and 5 min lower than 3, male, resuscitation in the delivery room, persistent pulmonary (PPHN). The rates of retinopathy of prematurity (ROP) and intraventricular hemorrhage (IVH) did not change significantly, whereas the rate of severe ROP and severe IVH increased slightly from 2001 to 2005. The rate of respiratory distress syndrome (RDS), patent ductus arteriosus (PDA), bronchopulmonary dysplasia (BPD) increased significantly from 1996 to 2005.
Conclusions: There have been some significant decreases in mortality for low birth weight preterm infants from 1996 to 2005, in particular extremely low birth weight preterm infants. But the rates of some complications increased.
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